Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISM_1519027 kDa outer membrane protein, putative; COG1651 Protein-disulfide isomerase. (248 aa)    
Predicted Functional Partners:
ISM_15195
Peptidase, M48 family protein; COG4783 Putative Zn-dependent protease, contains TPR repeats.
  
    0.807
ISM_07300
Thiol:disulfide interchange protein, DsbA family protein; COG1651 Protein-disulfide isomerase.
  
     0.732
ISM_15185
Hypothetical protein.
       0.693
ISM_14545
Disulfide bond formation protein, DsbB family protein.
 
 
 0.683
ISM_17545
COG1495 Disulfide bond formation protein DsbB; Belongs to the DsbB family.
  
 
 0.649
ISM_15200
Aminotransferase, classes I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase.
       0.582
ISM_15210
Penicillin-binding protein 1A; COG5009 Membrane carboxypeptidase/penicillin-binding protein.
 
     0.461
bamD
Competence lipoprotein ComL, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.424
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.406
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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