STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_15200Aminotransferase, classes I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (366 aa)    
Predicted Functional Partners:
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
    
 0.816
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
  
 0.720
ISM_09586
Malate dehydrogenase; COG0281 Malic enzyme.
  
 0.720
ISM_15195
Peptidase, M48 family protein; COG4783 Putative Zn-dependent protease, contains TPR repeats.
       0.690
ISM_14700
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
    
 0.685
ISM_08325
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
 0.646
ISM_15205
N-acetylmuramoyl-L-alanine amidase, family 3; COG0860 N-acetylmuramoyl-L-alanine amidase.
  
    0.646
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.622
ISM_05245
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.620
ISM_12920
COG0460 Homoserine dehydrogenase.
 
 0.605
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.