Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_15205N-acetylmuramoyl-L-alanine amidase, family 3; COG0860 N-acetylmuramoyl-L-alanine amidase. (410 aa)    
Predicted Functional Partners:
ISM_02405
Hypothetical protein; COG4942 Membrane-bound metallopeptidase.
 
 
 
 0.892
ISM_10136
Putative outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
    
   0.775
ISM_09971
Rhomboid family protein; COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).
 
 
   0.735
ISM_09596
Hypothetical protein; COG1204 Superfamily II helicase.
  
 0.729
ISM_16425
Hypothetical protein.
  
 0.729
ISM_15210
Penicillin-binding protein 1A; COG5009 Membrane carboxypeptidase/penicillin-binding protein.
 
   
 0.721
ISM_08330
Rhomboid family protein; COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).
   
   0.701
ISM_17785
COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).
   
   0.701
ISM_09986
Hypothetical protein; COG3409 Putative peptidoglycan-binding domain-containing protein.
    
 0.633
ISM_15200
Aminotransferase, classes I and II; COG0436 Aspartate/tyrosine/aromatic aminotransferase.
  
    0.630
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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