Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_15210Penicillin-binding protein 1A; COG5009 Membrane carboxypeptidase/penicillin-binding protein. (824 aa)    
Predicted Functional Partners:
ISM_02765
COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
 
 0.973
ISM_00145
COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
 
0.945
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
 
 
0.919
ISM_05675
D-alanyl-D-alaninecarboxypeptidase/D-alanyl-D- alanine-endopeptidase; COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4).
  
  
 0.893
ISM_08970
Penicillin-binding protein, 1A family protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
 
 
0.884
ISM_00855
COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.871
ISM_06915
Penicillin-binding protein 1C; COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC.
  
  
0.782
mrdB
Rod shape-determining protein MreD; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.732
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
   
 0.730
ISM_15205
N-acetylmuramoyl-L-alanine amidase, family 3; COG0860 N-acetylmuramoyl-L-alanine amidase.
 
   
 0.721
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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