STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_15285COG4564 Signal transduction histidine kinase. (474 aa)    
Predicted Functional Partners:
ISM_15280
DNA-binding response regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
  
  0.963
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
    
 0.785
ISM_15295
Hypothetical protein; COG4665 TRAP-type mannitol/chloroaromatic compound transport system, small permease component.
 
     0.781
ISM_15300
TRAP transporter, DctM subunit, putative; COG4664 TRAP-type mannitol/chloroaromatic compound transport system, large permease component.
 
     0.698
ISM_07425
Putative two-component system sensor histidine kinase; COG2203 FOG: GAF domain.
   
 0.697
ISM_05685
Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
    
  0.669
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
    
 0.637
ISM_15290
Bacterial extracellular solute-binding protein, family 7 protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
 
     0.573
ISM_04775
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
 
   
 0.559
ISM_05545
Histidine kinase/response regulator hybrid protein; COG2202 FOG: PAS/PAC domain.
 
   
 0.559
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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