Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_15305Hypothetical protein; COG0662 Mannose-6-phosphate isomerase. (112 aa)    
Predicted Functional Partners:
ISM_03530
Putative UDP-galactose phosphate transferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
 
 0.539
ISM_05610
COG1086 Predicted nucleoside-diphosphate sugar epimerases.
  
 
 0.473
ISM_03855
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.457
ISM_07410
COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.
  
 
 0.453
ISM_06910
Exopolysaccharide production protein exoY; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
 
 0.440
ISM_16685
COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
 
 0.440
gmd
NAD-dependent epimerase/dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.438
ISM_16730
Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase.
    
 0.425
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
  
  0.424
ISM_06830
Nucleotidyltransferase family protein; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).
  
 
  0.419
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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