| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_04830 | ISM_15425 | ISM_04830 | ISM_15425 | Porphyromonas-type peptidyl-arginine deiminase family protein; COG2957 Peptidylarginine deiminase and related enzymes; Belongs to the agmatine deiminase family. | COG0388 Predicted amidohydrolase. | 0.734 |
| ISM_06100 | ISM_08325 | ISM_06100 | ISM_08325 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.920 |
| ISM_06100 | ISM_09180 | ISM_06100 | ISM_09180 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG1012 NAD-dependent aldehyde dehydrogenases. | 0.794 |
| ISM_06100 | ISM_13635 | ISM_06100 | ISM_13635 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG0167 Dihydroorotate dehydrogenase. | 0.822 |
| ISM_06100 | ISM_14700 | ISM_06100 | ISM_14700 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.917 |
| ISM_06100 | ISM_15425 | ISM_06100 | ISM_15425 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG0388 Predicted amidohydrolase. | 0.677 |
| ISM_06100 | fur-2 | ISM_06100 | ISM_15430 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Ferric-uptake regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family. | 0.718 |
| ISM_07130 | ISM_15425 | ISM_07130 | ISM_15425 | Proteinase; COG0693 Putative intracellular protease/amidase. | COG0388 Predicted amidohydrolase. | 0.544 |
| ISM_08325 | ISM_06100 | ISM_08325 | ISM_06100 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.920 |
| ISM_08325 | ISM_09180 | ISM_08325 | ISM_09180 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG1012 NAD-dependent aldehyde dehydrogenases. | 0.800 |
| ISM_08325 | ISM_13635 | ISM_08325 | ISM_13635 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG0167 Dihydroorotate dehydrogenase. | 0.410 |
| ISM_08325 | ISM_14700 | ISM_08325 | ISM_14700 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.465 |
| ISM_08325 | ISM_15425 | ISM_08325 | ISM_15425 | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | COG0388 Predicted amidohydrolase. | 0.594 |
| ISM_09180 | ISM_06100 | ISM_09180 | ISM_06100 | COG1012 NAD-dependent aldehyde dehydrogenases. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.794 |
| ISM_09180 | ISM_08325 | ISM_09180 | ISM_08325 | COG1012 NAD-dependent aldehyde dehydrogenases. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.800 |
| ISM_09180 | ISM_14700 | ISM_09180 | ISM_14700 | COG1012 NAD-dependent aldehyde dehydrogenases. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.551 |
| ISM_09180 | ISM_15425 | ISM_09180 | ISM_15425 | COG1012 NAD-dependent aldehyde dehydrogenases. | COG0388 Predicted amidohydrolase. | 0.517 |
| ISM_13635 | ISM_06100 | ISM_13635 | ISM_06100 | COG0167 Dihydroorotate dehydrogenase. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.822 |
| ISM_13635 | ISM_08325 | ISM_13635 | ISM_08325 | COG0167 Dihydroorotate dehydrogenase. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.410 |
| ISM_13635 | ISM_14700 | ISM_13635 | ISM_14700 | COG0167 Dihydroorotate dehydrogenase. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.946 |