STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_15490Possible ribosomal protein S6 modification protein; COG4067 Uncharacterized protein conserved in archaea. (470 aa)    
Predicted Functional Partners:
ISM_13925
Succinylglutamate desuccinylase/aspartoacylase; COG3608 Predicted deacylase.
 
     0.830
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
    
 0.640
ISM_06475
COG3453 Uncharacterized protein conserved in bacteria.
     
  0.611
rplW
Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
    
   0.595
ISM_16310
Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters.
 
     0.562
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
       0.538
ISM_15495
Hypothetical protein.
       0.532
ISM_15500
SPFH domain/band 7 family protein; COG0330 Membrane protease subunits, stomatin/prohibitin homologs.
       0.531
cysC
Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate.
  
  
 0.488
ISM_05945
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
    
 0.439
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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