STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_15500SPFH domain/band 7 family protein; COG0330 Membrane protease subunits, stomatin/prohibitin homologs. (296 aa)    
Predicted Functional Partners:
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.981
ISM_15495
Hypothetical protein.
 
  
 0.971
ISM_08330
Rhomboid family protein; COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).
  
 0.752
ISM_06465
Peptidase, M16 family protein; COG0612 Predicted Zn-dependent peptidases.
  
 0.746
ISM_09971
Rhomboid family protein; COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).
   
 0.742
ISM_03090
Peptidase, M16 family protein; COG0612 Predicted Zn-dependent peptidases; Belongs to the peptidase M16 family.
   
 0.735
ISM_06460
Peptidase, M16 family protein; COG0612 Predicted Zn-dependent peptidases; Belongs to the peptidase M16 family.
   
 0.735
ISM_17785
COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).
   
 0.708
ISM_13465
Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
    
  0.647
ISM_12040
Membrane protein, putative.
   
 0.566
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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