STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_15610Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake. (241 aa)    
Predicted Functional Partners:
pstB
Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
  
 0.996
ISM_15600
COG0581 ABC-type phosphate transport system, permease component.
 
  
 0.992
ISM_15595
Phosphate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
  
 0.951
ISM_15590
COG0226 ABC-type phosphate transport system, periplasmic component.
 
  
 0.944
ISM_15615
Phosphate regulon transcriptional regulatory protein PhoB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
  
 0.773
ISM_15585
Phosphate regulon sensor histidine kinase, putative; COG0642 Signal transduction histidine kinase.
 
   
 0.761
ISM_06485
OmpA domain protein; COG0226 ABC-type phosphate transport system, periplasmic component.
 
  
 0.746
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
  
  
 0.509
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
     
 0.507
ISM_12905
Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain.
 
   
 0.496
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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