STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_15640Hypothetical protein; COG1522 Transcriptional regulators. (79 aa)    
Predicted Functional Partners:
ISM_15650
Autoinducer-binding transcriptional regulator, LuxR family protein; COG2771 DNA-binding HTH domain-containing proteins.
    
  0.605
ISM_15725
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 
 0.550
ISM_06025
Hypothetical protein.
  
     0.523
aroQ
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
       0.514
ISM_16505
Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases.
 
 
 0.467
ISM_15635
Probable transposase protein, Y4bF; COG2801 Transposase and inactivated derivatives.
       0.458
ISM_15630
Hypothetical protein.
       0.439
ISM_04045
Probable substrate-binding protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.
 
     0.417
ISM_04095
Benzoate-coenzyme A ligase; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
 
  
  0.417
ISM_06630
COG2198 FOG: HPt domain.
  
     0.413
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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