Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ISM_15650Autoinducer-binding transcriptional regulator, LuxR family protein; COG2771 DNA-binding HTH domain-containing proteins. (252 aa)    
Predicted Functional Partners:
aroQ
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
       0.844
ISM_10406
Metallo-beta-lactamase family protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
    
 
 0.726
ISM_03755
N-acylhomoserine lactone synthase; COG3916 N-acyl-L-homoserine lactone synthetase; Belongs to the autoinducer synthase family.
  
 
 0.675
ISM_00540
Endonuclease/exonuclease/phosphatase family protein.
  
     0.621
ISM_09921
Autoinducer-binding transcriptional regulator LuxR; COG2771 DNA-binding HTH domain-containing proteins.
   
 0.589
ISM_15280
DNA-binding response regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
   
 0.589
ISM_17000
Nitrate/nitrite regulatory protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
   
 0.589
ISM_17075
Putative nitrate/nitrite response regulator protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
   
 0.589
ISM_01270
Transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
   
 0.570
ISM_10720
Hypothetical protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
    
 
 0.554
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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