Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ISM_15670Phospholipase, patatin-like family protein; COG1752 Predicted esterase of the alpha-beta hydrolase superfamily. (341 aa)    
Predicted Functional Partners:
ISM_15675
COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
  
  0.752
ISM_14030
COG3243 Poly(3-hydroxyalkanoate) synthetase.
 
   
 0.657
ISM_07555
TRAG protein; COG3505 Type IV secretory pathway, VirD4 components.
    
   0.604
ISM_17295
Hypothetical protein.
    
   0.604
ISM_17825
Type IV secretion system coupling protein; COG3505 Type IV secretory pathway, VirD4 components.
    
   0.604
ISM_14040
COG5394 Uncharacterized protein conserved in bacteria.
 
     0.512
ISM_05905
AMP-binding enzyme; COG1022 Long-chain acyl-CoA synthetases (AMP-forming).
  
 
 0.510
ISM_00045
Hydrolase, alpha/beta fold family protein; COG2267 Lysophospholipase.
   
 
 0.508
ISM_08410
COG0112 Glycine/serine hydroxymethyltransferase.
   
   0.504
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
   0.504
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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