Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISM_15685DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. (207 aa)    
Predicted Functional Partners:
ISM_15690
Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
       0.678
ISM_15695
DSBA-like thioredoxin family protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.
       0.610
ISM_15710
COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
    
  0.452
nadE
NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.423
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
     
  0.422
ISM_09586
Malate dehydrogenase; COG0281 Malic enzyme.
     
  0.422
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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