| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_01725 | ISM_15690 | ISM_01725 | ISM_15690 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.910 |
| ISM_01725 | rplC | ISM_01725 | ISM_01840 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.999 |
| ISM_01725 | rplM | ISM_01725 | ISM_16295 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
| ISM_01725 | rplO | ISM_01725 | ISM_01705 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.999 |
| ISM_01725 | rplQ | ISM_01725 | ISM_01670 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | COG0203 Ribosomal protein L17. | 0.999 |
| ISM_01725 | rplX | ISM_01725 | ISM_01745 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.999 |
| ISM_01725 | rpsQ | ISM_01725 | ISM_01760 | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.999 |
| ISM_06040 | ISM_15690 | ISM_06040 | ISM_15690 | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.914 |
| ISM_15690 | ISM_01725 | ISM_15690 | ISM_01725 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. | 0.910 |
| ISM_15690 | ISM_06040 | ISM_15690 | ISM_06040 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. | 0.914 |
| ISM_15690 | ISM_16730 | ISM_15690 | ISM_16730 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | 0.908 |
| ISM_15690 | ISM_16740 | ISM_15690 | ISM_16740 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.927 |
| ISM_15690 | rplC | ISM_15690 | ISM_01840 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.890 |
| ISM_15690 | rplM | ISM_15690 | ISM_16295 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.892 |
| ISM_15690 | rplO | ISM_15690 | ISM_01705 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.891 |
| ISM_15690 | rplQ | ISM_15690 | ISM_01670 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | COG0203 Ribosomal protein L17. | 0.880 |
| ISM_15690 | rplX | ISM_15690 | ISM_01745 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.890 |
| ISM_15690 | rpsQ | ISM_15690 | ISM_01760 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.887 |
| ISM_16730 | ISM_15690 | ISM_16730 | ISM_15690 | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.908 |
| ISM_16730 | ISM_16740 | ISM_16730 | ISM_16740 | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.999 |