| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_08260 | ISM_15700 | Type I secretion membrane fusion protein, HlyD family protein; COG0845 Membrane-fusion protein. | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | 0.438 |
| ISM_09751 | ISM_15700 | Efflux transporter, RND family protein, MFP subunit; COG0845 Membrane-fusion protein. | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | 0.446 |
| ISM_15685 | ISM_15690 | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.674 |
| ISM_15685 | ISM_15695 | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | DSBA-like thioredoxin family protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | 0.627 |
| ISM_15685 | ISM_15700 | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | 0.400 |
| ISM_15685 | ISM_15710 | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.439 |
| ISM_15690 | ISM_15685 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.674 |
| ISM_15690 | ISM_15695 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | DSBA-like thioredoxin family protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | 0.810 |
| ISM_15690 | ISM_15700 | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | 0.615 |
| ISM_15695 | ISM_15685 | DSBA-like thioredoxin family protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.627 |
| ISM_15695 | ISM_15690 | DSBA-like thioredoxin family protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.810 |
| ISM_15695 | ISM_15700 | DSBA-like thioredoxin family protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | 0.607 |
| ISM_15700 | ISM_08260 | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | Type I secretion membrane fusion protein, HlyD family protein; COG0845 Membrane-fusion protein. | 0.438 |
| ISM_15700 | ISM_09751 | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | Efflux transporter, RND family protein, MFP subunit; COG0845 Membrane-fusion protein. | 0.446 |
| ISM_15700 | ISM_15685 | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.400 |
| ISM_15700 | ISM_15690 | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.615 |
| ISM_15700 | ISM_15695 | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | DSBA-like thioredoxin family protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis. | 0.607 |
| ISM_15700 | ISM_15710 | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.567 |
| ISM_15710 | ISM_15685 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.439 |
| ISM_15710 | ISM_15700 | COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Multidrug (bicyclomycin) efflux pump, Major facilitator superfamily(MFS); COG0477 Permeases of the major facilitator superfamily. | 0.567 |