Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_15810ABC transporter, inner membrane subunit; COG0767 ABC-type transport system involved in resistance to organic solvents, permease component. (261 aa)    
Predicted Functional Partners:
ISM_15815
ABC transporter, ATP-binding protein; COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component.
 
 0.999
ISM_01295
Hypothetical protein; COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component.
 
 0.996
ISM_08980
Toluene tolerance family protein; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component.
 
 
 0.957
ISM_10166
COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
   
 0.914
ISM_15805
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
       0.845
ISM_08985
VacJ lipoprotein, putative; COG2853 Surface lipoprotein.
 
   
 0.788
ISM_06985
ABC transporter, ATP-binding protein; COG1137 ABC-type (unclassified) transport system, ATPase component.
 
  
  0.644
ISM_15820
Hypothetical protein; COG2995 Uncharacterized paraquat-inducible protein A.
     
 0.635
bamA
Outer membrane protein, OMP85 family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
     0.606
ISM_15800
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
       0.595
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (16%) [HD]