Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_15825Hypothetical protein; COG1196 Chromosome segregation ATPases. (257 aa)    
Predicted Functional Partners:
ISM_15820
Hypothetical protein; COG2995 Uncharacterized paraquat-inducible protein A.
       0.666
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.651
ISM_15835
CvpA family protein; COG1286 Uncharacterized membrane protein, required for colicin V production.
       0.603
ISM_02045
Hypothetical protein.
  
     0.510
ISM_15805
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
       0.509
ISM_15925
Hypothetical protein.
  
     0.493
ISM_13530
Hypothetical protein.
  
     0.463
ISM_15840
COG3238 Uncharacterized protein conserved in bacteria.
       0.458
ISM_07940
Membrane protein, putative.
  
     0.455
ISM_02070
Hypothetical protein.
  
     0.424
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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