STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_15915Hypothetical protein; COG0591 Na+/proline symporter. (456 aa)    
Predicted Functional Partners:
ISM_08325
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
  
 0.972
ISM_16505
Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases.
 
     0.634
ISM_02165
COG3222 Uncharacterized protein conserved in bacteria.
 
     0.626
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.604
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
    
 0.584
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
  
  
 0.519
ISM_15910
ABC transporter, ATPase subunit; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.
       0.518
pxpA
Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
    0.508
ISM_14750
COG0372 Citrate synthase; Belongs to the citrate synthase family.
   
  
 0.504
ISM_04775
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
   
 
 0.496
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.