STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_15985Hypothetical protein; COG0500 SAM-dependent methyltransferases. (255 aa)    
Predicted Functional Partners:
ISM_15980
Hypothetical protein; COG4122 Predicted O-methyltransferase.
       0.787
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.723
ISM_15970
FeS assembly protein SufD; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
       0.678
ISM_15975
FeS assembly ATPase SufC; COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.
       0.678
ISM_15995
Hypothetical protein; COG0500 SAM-dependent methyltransferases.
 
    
0.663
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
 
 0.615
ISM_15990
Hypothetical protein.
       0.613
ISM_17225
Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components.
   
 
 0.590
ISM_16005
FeS assembly protein SufB; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
       0.577
ISM_16000
Hypothetical protein.
       0.562
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.