Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_16010Putative aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. (347 aa)    
Predicted Functional Partners:
ISM_15105
Hypothetical protein; COG0822 NifU homolog involved in Fe-S cluster formation.
  
 0.996
ISM_16015
Iron-sulfur cluster assembly transcription factor IscR, putative; COG1959 Predicted transcriptional regulator.
 
 
 0.988
ISM_16985
SirA family protein; COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.
   
 0.986
ISM_15460
Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
 
 
 0.951
ISM_07105
Iron-sulfur cluster-binding protein; COG0633 Ferredoxin.
 
 0.944
ISM_10646
Thiamine biosynthesis protein ThiF; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
   
 0.943
ISM_08180
Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
  
 0.910
ISM_08760
Thiosulfate sulfurtransferase, putative; COG2897 Rhodanese-related sulfurtransferase.
  
 0.910
ISM_02850
nifU domain protein; COG0694 Thioredoxin-like proteins and domains.
 
 
 0.906
ISM_16005
FeS assembly protein SufB; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
  
  
 0.879
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.