Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_16020Hypothetical protein; COG2945 Predicted hydrolase of the alpha/beta superfamily. (217 aa)    
Predicted Functional Partners:
ISM_16025
Hypothetical protein.
       0.845
ISM_06785
Transporter, Tim44 family protein; COG4395 Uncharacterized protein conserved in bacteria.
  
     0.663
ISM_16015
Iron-sulfur cluster assembly transcription factor IscR, putative; COG1959 Predicted transcriptional regulator.
       0.661
ISM_12070
COG3820 Uncharacterized protein conserved in bacteria.
  
     0.627
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.565
ISM_16010
Putative aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
       0.545
bamD
Competence lipoprotein ComL, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
     0.538
ISM_16005
FeS assembly protein SufB; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.
       0.534
ISM_12425
COG3814 Uncharacterized protein conserved in bacteria.
  
     0.531
ISM_14450
COG3807 Uncharacterized protein conserved in bacteria.
  
     0.508
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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