| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_04690 | ISM_08755 | ISM_04690 | ISM_08755 | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.840 |
| ISM_04690 | hisC | ISM_04690 | ISM_02500 | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.927 |
| ISM_04690 | hutH | ISM_04690 | ISM_05635 | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | COG2986 Histidine ammonia-lyase. | 0.664 |
| ISM_04690 | katG | ISM_04690 | ISM_16225 | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Fungal/archaeal/bacterial haem catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.910 |
| ISM_06815 | ISM_09356 | ISM_06815 | ISM_09356 | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.695 |
| ISM_06815 | katG | ISM_06815 | ISM_16225 | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | Fungal/archaeal/bacterial haem catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.672 |
| ISM_07130 | ISM_09356 | ISM_07130 | ISM_09356 | Proteinase; COG0693 Putative intracellular protease/amidase. | Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.404 |
| ISM_07130 | katG | ISM_07130 | ISM_16225 | Proteinase; COG0693 Putative intracellular protease/amidase. | Fungal/archaeal/bacterial haem catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.579 |
| ISM_07435 | ISM_09356 | ISM_07435 | ISM_09356 | COG3118 Thioredoxin domain-containing protein. | Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.486 |
| ISM_07435 | katG | ISM_07435 | ISM_16225 | COG3118 Thioredoxin domain-containing protein. | Fungal/archaeal/bacterial haem catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.657 |
| ISM_08755 | ISM_04690 | ISM_08755 | ISM_04690 | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.840 |
| ISM_08755 | hisC | ISM_08755 | ISM_02500 | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.840 |
| ISM_08755 | hutH | ISM_08755 | ISM_05635 | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | COG2986 Histidine ammonia-lyase. | 0.778 |
| ISM_08755 | katG | ISM_08755 | ISM_16225 | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | Fungal/archaeal/bacterial haem catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.915 |
| ISM_09356 | ISM_06815 | ISM_09356 | ISM_06815 | Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | 0.695 |
| ISM_09356 | ISM_07130 | ISM_09356 | ISM_07130 | Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Proteinase; COG0693 Putative intracellular protease/amidase. | 0.404 |
| ISM_09356 | ISM_07435 | ISM_09356 | ISM_07435 | Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | COG3118 Thioredoxin domain-containing protein. | 0.486 |
| ISM_09356 | katG | ISM_09356 | ISM_16225 | Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Fungal/archaeal/bacterial haem catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.696 |
| ISM_16220 | katG | ISM_16220 | ISM_16225 | Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Fungal/archaeal/bacterial haem catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.509 |
| clpS | katG | ISM_07965 | ISM_16225 | ATP-dependent Clp protease, adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | Fungal/archaeal/bacterial haem catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.511 |