| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_06100 | ISM_16230 | ISM_06100 | ISM_16230 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | COG1814 Uncharacterized membrane protein. | 0.452 |
| ISM_06100 | gatC | ISM_06100 | ISM_02155 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.480 |
| ISM_06100 | guaB | ISM_06100 | ISM_14860 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.979 |
| ISM_09916 | ISM_16230 | ISM_09916 | ISM_16230 | GatB/YqeY domain protein. | COG1814 Uncharacterized membrane protein. | 0.499 |
| ISM_09916 | gatA | ISM_09916 | ISM_02150 | GatB/YqeY domain protein. | glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | 0.559 |
| ISM_09916 | gatC | ISM_09916 | ISM_02155 | GatB/YqeY domain protein. | glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.605 |
| ISM_12040 | ISM_16230 | ISM_12040 | ISM_16230 | Membrane protein, putative. | COG1814 Uncharacterized membrane protein. | 0.545 |
| ISM_12040 | gmk | ISM_12040 | ISM_15575 | Membrane protein, putative. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.579 |
| ISM_16230 | ISM_06100 | ISM_16230 | ISM_06100 | COG1814 Uncharacterized membrane protein. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.452 |
| ISM_16230 | ISM_09916 | ISM_16230 | ISM_09916 | COG1814 Uncharacterized membrane protein. | GatB/YqeY domain protein. | 0.499 |
| ISM_16230 | ISM_12040 | ISM_16230 | ISM_12040 | COG1814 Uncharacterized membrane protein. | Membrane protein, putative. | 0.545 |
| ISM_16230 | gatA | ISM_16230 | ISM_02150 | COG1814 Uncharacterized membrane protein. | glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | 0.499 |
| ISM_16230 | gatC | ISM_16230 | ISM_02155 | COG1814 Uncharacterized membrane protein. | glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.499 |
| ISM_16230 | gmk | ISM_16230 | ISM_15575 | COG1814 Uncharacterized membrane protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.499 |
| ISM_16230 | guaB | ISM_16230 | ISM_14860 | COG1814 Uncharacterized membrane protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.499 |
| ISM_16230 | katG | ISM_16230 | ISM_16225 | COG1814 Uncharacterized membrane protein. | Fungal/archaeal/bacterial haem catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. | 0.470 |
| gatA | ISM_09916 | ISM_02150 | ISM_09916 | glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | GatB/YqeY domain protein. | 0.559 |
| gatA | ISM_16230 | ISM_02150 | ISM_16230 | glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | COG1814 Uncharacterized membrane protein. | 0.499 |
| gatA | gatC | ISM_02150 | ISM_02155 | glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). | glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.999 |
| gatC | ISM_06100 | ISM_02155 | ISM_06100 | glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.480 |