| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_09190 | ISM_16260 | ISM_09190 | ISM_16260 | COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | 0.752 |
| ISM_09190 | secY | ISM_09190 | ISM_01700 | COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.499 |
| ISM_16260 | ISM_09190 | ISM_16260 | ISM_09190 | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | 0.752 |
| ISM_16260 | ISM_16265 | ISM_16260 | ISM_16265 | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | Putative outer membrane protein; COG2067 Long-chain fatty acid transport protein. | 0.496 |
| ISM_16260 | ISM_16575 | ISM_16260 | ISM_16575 | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | 0.750 |
| ISM_16260 | guaA | ISM_16260 | ISM_16255 | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.482 |
| ISM_16260 | secY | ISM_16260 | ISM_01700 | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.423 |
| ISM_16265 | ISM_16260 | ISM_16265 | ISM_16260 | Putative outer membrane protein; COG2067 Long-chain fatty acid transport protein. | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | 0.496 |
| ISM_16265 | guaA | ISM_16265 | ISM_16255 | Putative outer membrane protein; COG2067 Long-chain fatty acid transport protein. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.473 |
| ISM_16575 | ISM_16260 | ISM_16575 | ISM_16260 | COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | 0.750 |
| ISM_16575 | secY | ISM_16575 | ISM_01700 | COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.423 |
| guaA | ISM_16260 | ISM_16255 | ISM_16260 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | 0.482 |
| guaA | ISM_16265 | ISM_16255 | ISM_16265 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative outer membrane protein; COG2067 Long-chain fatty acid transport protein. | 0.473 |
| guaA | secY | ISM_16255 | ISM_01700 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.443 |
| secY | ISM_09190 | ISM_01700 | ISM_09190 | Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | 0.499 |
| secY | ISM_16260 | ISM_01700 | ISM_16260 | Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | Membrane protein, putative; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | 0.423 |
| secY | ISM_16575 | ISM_01700 | ISM_16575 | Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. | 0.423 |
| secY | guaA | ISM_01700 | ISM_16255 | Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.443 |