| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_11555 | ISM_16310 | ISM_11555 | ISM_16310 | Hypothetical protein. | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | 0.441 |
| ISM_15490 | ISM_16310 | ISM_15490 | ISM_16310 | Possible ribosomal protein S6 modification protein; COG4067 Uncharacterized protein conserved in archaea. | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | 0.562 |
| ISM_15490 | ISM_17225 | ISM_15490 | ISM_17225 | Possible ribosomal protein S6 modification protein; COG4067 Uncharacterized protein conserved in archaea. | Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components. | 0.434 |
| ISM_15725 | ISM_16310 | ISM_15725 | ISM_16310 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | 0.497 |
| ISM_16310 | ISM_11555 | ISM_16310 | ISM_11555 | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | Hypothetical protein. | 0.441 |
| ISM_16310 | ISM_15490 | ISM_16310 | ISM_15490 | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | Possible ribosomal protein S6 modification protein; COG4067 Uncharacterized protein conserved in archaea. | 0.562 |
| ISM_16310 | ISM_15725 | ISM_16310 | ISM_15725 | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.497 |
| ISM_16310 | ISM_16315 | ISM_16310 | ISM_16315 | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | Thioesterase family protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism. | 0.776 |
| ISM_16310 | ISM_16320 | ISM_16310 | ISM_16320 | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.562 |
| ISM_16310 | ISM_17225 | ISM_16310 | ISM_17225 | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components. | 0.444 |
| ISM_16310 | lepA | ISM_16310 | ISM_13940 | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.425 |
| ISM_16315 | ISM_16310 | ISM_16315 | ISM_16310 | Thioesterase family protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism. | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | 0.776 |
| ISM_16315 | ISM_16320 | ISM_16315 | ISM_16320 | Thioesterase family protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism. | COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.570 |
| ISM_16320 | ISM_16310 | ISM_16320 | ISM_16310 | COG1024 Enoyl-CoA hydratase/carnithine racemase. | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | 0.562 |
| ISM_16320 | ISM_16315 | ISM_16320 | ISM_16315 | COG1024 Enoyl-CoA hydratase/carnithine racemase. | Thioesterase family protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism. | 0.570 |
| ISM_17225 | ISM_15490 | ISM_17225 | ISM_15490 | Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components. | Possible ribosomal protein S6 modification protein; COG4067 Uncharacterized protein conserved in archaea. | 0.434 |
| ISM_17225 | ISM_16310 | ISM_17225 | ISM_16310 | Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components. | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | 0.444 |
| lepA | ISM_16310 | ISM_13940 | ISM_16310 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Magnesium transporter, CorA family protein; COG0598 Mg2+ and Co2+ transporters. | 0.425 |
