| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_02615 | ISM_05255 | ISM_02615 | ISM_05255 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.929 |
| ISM_02615 | ISM_10930 | ISM_02615 | ISM_10930 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.930 |
| ISM_02615 | ISM_13350 | ISM_02615 | ISM_13350 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | COG0021 Transketolase; Belongs to the transketolase family. | 0.962 |
| ISM_02615 | eno | ISM_02615 | ISM_16480 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.997 |
| ISM_02615 | gpmI | ISM_02615 | ISM_02400 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.586 |
| ISM_02615 | pgi | ISM_02615 | ISM_16490 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.984 |
| ISM_02615 | pgk | ISM_02615 | ISM_04660 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.971 |
| ISM_02615 | rplD | ISM_02615 | ISM_01830 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.894 |
| ISM_02615 | tpiA | ISM_02615 | ISM_15455 | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.949 |
| ISM_05255 | ISM_02615 | ISM_05255 | ISM_02615 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.929 |
| ISM_05255 | ISM_10930 | ISM_05255 | ISM_10930 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.850 |
| ISM_05255 | ISM_13030 | ISM_05255 | ISM_13030 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.617 |
| ISM_05255 | ISM_13350 | ISM_05255 | ISM_13350 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | COG0021 Transketolase; Belongs to the transketolase family. | 0.961 |
| ISM_05255 | eno | ISM_05255 | ISM_16480 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.986 |
| ISM_05255 | gpmI | ISM_05255 | ISM_02400 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.480 |
| ISM_05255 | pgi | ISM_05255 | ISM_16490 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.939 |
| ISM_05255 | pgk | ISM_05255 | ISM_04660 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | COG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.998 |
| ISM_05255 | tpiA | ISM_05255 | ISM_15455 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.997 |
| ISM_10930 | ISM_02615 | ISM_10930 | ISM_02615 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.930 |
| ISM_10930 | ISM_05255 | ISM_10930 | ISM_05255 | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.850 |