STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_16505Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases. (327 aa)    
Predicted Functional Partners:
ISM_02165
COG3222 Uncharacterized protein conserved in bacteria.
 
     0.803
ISM_05560
Glycosyl transferase, group 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis.
 
     0.790
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolaseII, putative; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
 
  0.727
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
    
 0.708
ISM_13525
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
    
 0.664
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
       0.637
ISM_15915
Hypothetical protein; COG0591 Na+/proline symporter.
 
     0.634
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
       0.606
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 
 0.543
ISM_12890
Hypothetical protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.
    
 0.536
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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