Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISM_16510Peptidase, M48 family protein; COG0501 Zn-dependent protease with chaperone function. (227 aa)    
Predicted Functional Partners:
ISM_00035
Hypothetical protein; COG0457 FOG: TPR repeat.
   
 0.766
ISM_02405
Hypothetical protein; COG4942 Membrane-bound metallopeptidase.
 
 
   0.749
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolaseII, putative; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.712
ISM_02410
Carboxyl-terminal protease family protein; COG0793 Periplasmic protease; Belongs to the peptidase S41A family.
   
 
 0.659
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
  
 
  0.646
ISM_02460
COG1360 Flagellar motor protein.
    
   0.576
ISM_02780
Hypothetical protein.
  
     0.549
ISM_16505
Radical SAM domain protein; COG0535 Predicted Fe-S oxidoreductases.
       0.531
ISM_05580
Hypothetical protein.
  
     0.521
ISM_00200
Hypothetical protein.
  
     0.509
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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