Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_16530Hypothetical protein. (97 aa)    
Predicted Functional Partners:
ISM_16535
Glutamate-ammonia ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
  
    0.853
ISM_09316
COG3313 Predicted Fe-S protein.
  
     0.738
ISM_15125
Hypothetical protein.
  
     0.698
ISM_15120
metF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase.
  
     0.695
ISM_13445
Hypothetical protein.
  
     0.685
ISM_00200
Hypothetical protein.
  
     0.646
ISM_16540
RDD family protein; COG1714 Predicted membrane protein/domain.
       0.633
ISM_13545
COG0642 Signal transduction histidine kinase.
  
     0.563
ISM_16250
COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family.
  
     0.547
ISM_02190
Hypothetical protein; COG0173 Aspartyl-tRNA synthetase.
  
     0.537
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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