STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_16610Trk system potassium uptake protein TrkH; COG0168 Trk-type K+ transport systems, membrane components. (506 aa)    
Predicted Functional Partners:
ISM_16615
Potassium uptake transporter, NAD-binding subunit, TrkA; COG0569 K+ transport systems, NAD-binding component.
 
 
 0.993
ISM_16630
Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.
       0.665
hflX
GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
       0.645
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
       0.645
ISM_16645
tRNA-dihydrouridine synthase, putative; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
     
 0.531
ISM_16625
Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
       0.528
ISM_16640
Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific.
       0.523
ISM_16620
Hypothetical protein.
       0.516
ISM_06430
Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.513
ISM_10830
Hypothetical protein; COG0477 Permeases of the major facilitator superfamily.
  
     0.493
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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