STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_16610Trk system potassium uptake protein TrkH; COG0168 Trk-type K+ transport systems, membrane components. (506 aa)    
Predicted Functional Partners:
ISM_16615
Potassium uptake transporter, NAD-binding subunit, TrkA; COG0569 K+ transport systems, NAD-binding component.
 
 
 0.998
ISM_16630
Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.
     
 0.694
hflX
GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
       0.662
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
       0.662
ISM_16625
Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
       0.528
ISM_16620
Hypothetical protein.
       0.516
ISM_17225
Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components.
   
 
 0.516
ISM_16640
Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific.
       0.512
ISM_16645
tRNA-dihydrouridine synthase, putative; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.512
ISM_10830
Hypothetical protein; COG0477 Permeases of the major facilitator superfamily.
  
     0.493
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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