STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_16635Nitrogen regulation protein NtrC; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. (447 aa)    
Predicted Functional Partners:
ISM_16640
Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific.
 0.999
ISM_16630
Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.
 
 0.861
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
  
 0.854
ISM_16645
tRNA-dihydrouridine synthase, putative; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
     
 0.793
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
  
 0.719
ISM_03055
COG0642 Signal transduction histidine kinase.
 
 0.709
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
  
 0.696
ISM_12905
Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain.
 
 
 0.679
ISM_09296
Putative two-component sensor histidine kinase protein; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system.
 0.661
ISM_13495
C4-dicarboxylate transport sensor protein DctB, putative; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system.
 0.658
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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