| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_00215 | ISM_03055 | Hypothetical protein; COG2199 FOG: GGDEF domain. | COG0642 Signal transduction histidine kinase. | 0.762 |
| ISM_00215 | ISM_06925 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.996 |
| ISM_00215 | ISM_12905 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain. | 0.861 |
| ISM_00215 | ISM_15585 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Phosphate regulon sensor histidine kinase, putative; COG0642 Signal transduction histidine kinase. | 0.577 |
| ISM_00215 | ISM_16625 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.668 |
| ISM_00215 | ISM_16630 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation. | 0.480 |
| ISM_00215 | ISM_16635 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Nitrogen regulation protein NtrC; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.668 |
| ISM_00215 | ISM_16640 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.437 |
| ISM_03055 | ISM_00215 | COG0642 Signal transduction histidine kinase. | Hypothetical protein; COG2199 FOG: GGDEF domain. | 0.762 |
| ISM_03055 | ISM_06925 | COG0642 Signal transduction histidine kinase. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.890 |
| ISM_03055 | ISM_12905 | COG0642 Signal transduction histidine kinase. | Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain. | 0.657 |
| ISM_03055 | ISM_15585 | COG0642 Signal transduction histidine kinase. | Phosphate regulon sensor histidine kinase, putative; COG0642 Signal transduction histidine kinase. | 0.635 |
| ISM_03055 | ISM_16625 | COG0642 Signal transduction histidine kinase. | Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.579 |
| ISM_03055 | ISM_16630 | COG0642 Signal transduction histidine kinase. | Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation. | 0.524 |
| ISM_03055 | ISM_16635 | COG0642 Signal transduction histidine kinase. | Nitrogen regulation protein NtrC; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.611 |
| ISM_03055 | ISM_16640 | COG0642 Signal transduction histidine kinase. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.605 |
| ISM_06925 | ISM_00215 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Hypothetical protein; COG2199 FOG: GGDEF domain. | 0.996 |
| ISM_06925 | ISM_03055 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | COG0642 Signal transduction histidine kinase. | 0.890 |
| ISM_06925 | ISM_12905 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain. | 0.989 |
| ISM_06925 | ISM_15585 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Phosphate regulon sensor histidine kinase, putative; COG0642 Signal transduction histidine kinase. | 0.957 |