| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_04850 | ISM_06925 | COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.873 |
| ISM_04850 | ISM_16640 | COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.893 |
| ISM_05410 | ISM_16640 | COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.994 |
| ISM_06925 | ISM_04850 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.873 |
| ISM_06925 | ISM_09291 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Hypothetical protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.854 |
| ISM_06925 | ISM_11185 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.873 |
| ISM_06925 | ISM_13500 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.874 |
| ISM_06925 | ISM_16625 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.854 |
| ISM_06925 | ISM_16635 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Nitrogen regulation protein NtrC; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.854 |
| ISM_06925 | ISM_16640 | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.941 |
| ISM_08965 | ISM_16640 | COG0347 Nitrogen regulatory protein PII. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.978 |
| ISM_09291 | ISM_06925 | Hypothetical protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.854 |
| ISM_09291 | ISM_16640 | Hypothetical protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.903 |
| ISM_11185 | ISM_06925 | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.873 |
| ISM_11185 | ISM_16640 | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.900 |
| ISM_13500 | ISM_06925 | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.874 |
| ISM_13500 | ISM_16640 | C4-dicarboxylate transport transcriptional regulatory protein DctD; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.926 |
| ISM_16625 | ISM_06925 | Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.854 |
| ISM_16625 | ISM_16635 | Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Nitrogen regulation protein NtrC; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | 0.631 |
| ISM_16625 | ISM_16640 | Nitrogen assimilation regulatory protein NtrX; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains. | Nitrogen regulation protein NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific. | 0.955 |