| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_03855 | ISM_03865 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.999 |
| ISM_03855 | ISM_03870 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | 0.999 |
| ISM_03855 | ISM_16700 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | Polysaccharide biosynthesis protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid. | 0.838 |
| ISM_03855 | ISM_16705 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | Glycosyl transferase, group 1 family protein; COG0438 Glycosyltransferase. | 0.566 |
| ISM_03855 | ISM_16730 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | 0.423 |
| ISM_03865 | ISM_03855 | COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.999 |
| ISM_03865 | ISM_03870 | COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | 0.999 |
| ISM_03865 | ISM_16700 | COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | Polysaccharide biosynthesis protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid. | 0.839 |
| ISM_03870 | ISM_03855 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. | 0.999 |
| ISM_03870 | ISM_03865 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.999 |
| ISM_03870 | ISM_16700 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | Polysaccharide biosynthesis protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid. | 0.839 |
| ISM_03870 | ISM_16705 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | Glycosyl transferase, group 1 family protein; COG0438 Glycosyltransferase. | 0.429 |
| ISM_16690 | ISM_16695 | Exopolysaccharide biosynthesis domain protein; COG0532 Translation initiation factor 2 (IF-2; GTPase). | Chain length determinant protein, putative; COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis. | 0.947 |
| ISM_16690 | ISM_16700 | Exopolysaccharide biosynthesis domain protein; COG0532 Translation initiation factor 2 (IF-2; GTPase). | Polysaccharide biosynthesis protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid. | 0.816 |
| ISM_16690 | ISM_16705 | Exopolysaccharide biosynthesis domain protein; COG0532 Translation initiation factor 2 (IF-2; GTPase). | Glycosyl transferase, group 1 family protein; COG0438 Glycosyltransferase. | 0.762 |
| ISM_16690 | ISM_16730 | Exopolysaccharide biosynthesis domain protein; COG0532 Translation initiation factor 2 (IF-2; GTPase). | Non-ribosomal peptide synthetase; COG0223 Methionyl-tRNA formyltransferase. | 0.797 |
| ISM_16690 | ISM_16740 | Exopolysaccharide biosynthesis domain protein; COG0532 Translation initiation factor 2 (IF-2; GTPase). | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.737 |
| ISM_16690 | ISM_16745 | Exopolysaccharide biosynthesis domain protein; COG0532 Translation initiation factor 2 (IF-2; GTPase). | Membrane protein, putative. | 0.787 |
| ISM_16690 | ISM_16750 | Exopolysaccharide biosynthesis domain protein; COG0532 Translation initiation factor 2 (IF-2; GTPase). | Glycosyl transferase, WecB/TagA/CpsF family protein; COG1922 Teichoic acid biosynthesis proteins; Belongs to the glycosyltransferase 26 family. | 0.797 |
| ISM_16695 | ISM_16690 | Chain length determinant protein, putative; COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis. | Exopolysaccharide biosynthesis domain protein; COG0532 Translation initiation factor 2 (IF-2; GTPase). | 0.947 |