| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_03915 | ISM_16845 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.581 |
| ISM_03915 | ISM_16850 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | 0.423 |
| ISM_03915 | ISM_16955 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.997 |
| ISM_09751 | ISM_16850 | Efflux transporter, RND family protein, MFP subunit; COG0845 Membrane-fusion protein. | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | 0.500 |
| ISM_16840 | ISM_16845 | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.802 |
| ISM_16840 | ISM_16850 | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | 0.488 |
| ISM_16840 | ISM_16855 | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.508 |
| ISM_16845 | ISM_03915 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.581 |
| ISM_16845 | ISM_16840 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | 0.802 |
| ISM_16845 | ISM_16850 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | 0.475 |
| ISM_16845 | ISM_16855 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.514 |
| ISM_16845 | ISM_16955 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.581 |
| ISM_16850 | ISM_03915 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.423 |
| ISM_16850 | ISM_09751 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | Efflux transporter, RND family protein, MFP subunit; COG0845 Membrane-fusion protein. | 0.500 |
| ISM_16850 | ISM_16840 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | 0.488 |
| ISM_16850 | ISM_16845 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.475 |
| ISM_16850 | ISM_16855 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.628 |
| ISM_16850 | ISM_16955 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.423 |
| ISM_16855 | ISM_16840 | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | 0.508 |
| ISM_16855 | ISM_16845 | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.514 |