| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_06675 | ISM_09586 | ISM_06675 | ISM_09586 | Phosphate acetyltransferase; COG0281 Malic enzyme. | Malate dehydrogenase; COG0281 Malic enzyme. | 0.786 |
| ISM_06675 | ISM_16845 | ISM_06675 | ISM_16845 | Phosphate acetyltransferase; COG0281 Malic enzyme. | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.428 |
| ISM_06675 | ISM_16855 | ISM_06675 | ISM_16855 | Phosphate acetyltransferase; COG0281 Malic enzyme. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.426 |
| ISM_06675 | nadE | ISM_06675 | ISM_02210 | Phosphate acetyltransferase; COG0281 Malic enzyme. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.697 |
| ISM_09586 | ISM_06675 | ISM_09586 | ISM_06675 | Malate dehydrogenase; COG0281 Malic enzyme. | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.786 |
| ISM_09586 | ISM_16845 | ISM_09586 | ISM_16845 | Malate dehydrogenase; COG0281 Malic enzyme. | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.428 |
| ISM_09586 | ISM_16855 | ISM_09586 | ISM_16855 | Malate dehydrogenase; COG0281 Malic enzyme. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.426 |
| ISM_09586 | nadE | ISM_09586 | ISM_02210 | Malate dehydrogenase; COG0281 Malic enzyme. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.697 |
| ISM_16725 | ISM_16855 | ISM_16725 | ISM_16855 | COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; Belongs to the P-Pant transferase superfamily. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.455 |
| ISM_16840 | ISM_16845 | ISM_16840 | ISM_16845 | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.802 |
| ISM_16840 | ISM_16850 | ISM_16840 | ISM_16850 | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | 0.488 |
| ISM_16840 | ISM_16855 | ISM_16840 | ISM_16855 | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.508 |
| ISM_16845 | ISM_06675 | ISM_16845 | ISM_06675 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | Phosphate acetyltransferase; COG0281 Malic enzyme. | 0.428 |
| ISM_16845 | ISM_09586 | ISM_16845 | ISM_09586 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | Malate dehydrogenase; COG0281 Malic enzyme. | 0.428 |
| ISM_16845 | ISM_16840 | ISM_16845 | ISM_16840 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | 0.802 |
| ISM_16845 | ISM_16850 | ISM_16845 | ISM_16850 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | 0.475 |
| ISM_16845 | ISM_16855 | ISM_16845 | ISM_16855 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.514 |
| ISM_16850 | ISM_16840 | ISM_16850 | ISM_16840 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | 0.488 |
| ISM_16850 | ISM_16845 | ISM_16850 | ISM_16845 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.475 |
| ISM_16850 | ISM_16855 | ISM_16850 | ISM_16855 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.628 |