| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_01205 | ISM_16855 | ISM_01205 | ISM_16855 | Sensor histidine kinase; COG0591 Na+/proline symporter. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.435 |
| ISM_04990 | ISM_16855 | ISM_04990 | ISM_16855 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.403 |
| ISM_04990 | nadE | ISM_04990 | ISM_02210 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | NAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.546 |
| ISM_07655 | ISM_16855 | ISM_07655 | ISM_16855 | COG3550 Uncharacterized protein related to capsule biosynthesis enzymes. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.604 |
| ISM_07665 | ISM_16855 | ISM_07665 | ISM_16855 | HipA protein; COG3550 Uncharacterized protein related to capsule biosynthesis enzymes. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.604 |
| ISM_14245 | ISM_16855 | ISM_14245 | ISM_16855 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.411 |
| ISM_16725 | ISM_16855 | ISM_16725 | ISM_16855 | COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; Belongs to the P-Pant transferase superfamily. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.455 |
| ISM_16840 | ISM_16845 | ISM_16840 | ISM_16845 | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.810 |
| ISM_16840 | ISM_16850 | ISM_16840 | ISM_16850 | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | 0.491 |
| ISM_16840 | ISM_16855 | ISM_16840 | ISM_16855 | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.486 |
| ISM_16845 | ISM_16840 | ISM_16845 | ISM_16840 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | 0.810 |
| ISM_16845 | ISM_16850 | ISM_16845 | ISM_16850 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | 0.475 |
| ISM_16845 | ISM_16855 | ISM_16845 | ISM_16855 | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.621 |
| ISM_16850 | ISM_16840 | ISM_16850 | ISM_16840 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase). | 0.491 |
| ISM_16850 | ISM_16845 | ISM_16850 | ISM_16845 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). | 0.475 |
| ISM_16850 | ISM_16855 | ISM_16850 | ISM_16855 | Drug resistance transporter, Bcr/CflA family protein; COG0477 Permeases of the major facilitator superfamily. | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | 0.643 |
| ISM_16855 | ISM_01205 | ISM_16855 | ISM_01205 | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | Sensor histidine kinase; COG0591 Na+/proline symporter. | 0.435 |
| ISM_16855 | ISM_04990 | ISM_16855 | ISM_04990 | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.403 |
| ISM_16855 | ISM_07655 | ISM_16855 | ISM_07655 | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | COG3550 Uncharacterized protein related to capsule biosynthesis enzymes. | 0.604 |
| ISM_16855 | ISM_07665 | ISM_16855 | ISM_07665 | DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. | HipA protein; COG3550 Uncharacterized protein related to capsule biosynthesis enzymes. | 0.604 |