Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_16860Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (552 aa)    
Predicted Functional Partners:
betI
Transcriptional regulator, BetI; Repressor involved in choline regulation of the bet genes.
 
 
 0.875
ISM_16865
COG3119 Arylsulfatase A and related enzymes.
     
 0.785
ISM_04860
WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat.
  
 0.717
ISM_00035
Hypothetical protein; COG0457 FOG: TPR repeat.
    
 0.702
ISM_08180
Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
    
 0.628
ISM_02565
Hypothetical protein; COG2010 Cytochrome c, mono- and diheme variants.
   
   0.589
ISM_10456
COG2010 Cytochrome c, mono- and diheme variants.
   
   0.589
ISM_13230
COG2010 Cytochrome c, mono- and diheme variants.
   
   0.589
ISM_17500
Probable c-type cytochrome; COG2010 Cytochrome c, mono- and diheme variants.
   
   0.589
ISM_03915
2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
   
 
  0.550
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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