| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_00035 | ISM_04860 | ISM_00035 | ISM_04860 | Hypothetical protein; COG0457 FOG: TPR repeat. | WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat. | 0.943 |
| ISM_00035 | ISM_08180 | ISM_00035 | ISM_08180 | Hypothetical protein; COG0457 FOG: TPR repeat. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.401 |
| ISM_00035 | ISM_16860 | ISM_00035 | ISM_16860 | Hypothetical protein; COG0457 FOG: TPR repeat. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.702 |
| ISM_02565 | ISM_03915 | ISM_02565 | ISM_03915 | Hypothetical protein; COG2010 Cytochrome c, mono- and diheme variants. | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | 0.588 |
| ISM_02565 | ISM_04860 | ISM_02565 | ISM_04860 | Hypothetical protein; COG2010 Cytochrome c, mono- and diheme variants. | WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat. | 0.720 |
| ISM_02565 | ISM_08180 | ISM_02565 | ISM_08180 | Hypothetical protein; COG2010 Cytochrome c, mono- and diheme variants. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.597 |
| ISM_02565 | ISM_16860 | ISM_02565 | ISM_16860 | Hypothetical protein; COG2010 Cytochrome c, mono- and diheme variants. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.589 |
| ISM_03915 | ISM_02565 | ISM_03915 | ISM_02565 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | Hypothetical protein; COG2010 Cytochrome c, mono- and diheme variants. | 0.588 |
| ISM_03915 | ISM_10456 | ISM_03915 | ISM_10456 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | COG2010 Cytochrome c, mono- and diheme variants. | 0.588 |
| ISM_03915 | ISM_13230 | ISM_03915 | ISM_13230 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | COG2010 Cytochrome c, mono- and diheme variants. | 0.588 |
| ISM_03915 | ISM_16860 | ISM_03915 | ISM_16860 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.550 |
| ISM_03915 | ISM_17500 | ISM_03915 | ISM_17500 | 2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. | Probable c-type cytochrome; COG2010 Cytochrome c, mono- and diheme variants. | 0.588 |
| ISM_04860 | ISM_00035 | ISM_04860 | ISM_00035 | WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat. | Hypothetical protein; COG0457 FOG: TPR repeat. | 0.943 |
| ISM_04860 | ISM_02565 | ISM_04860 | ISM_02565 | WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat. | Hypothetical protein; COG2010 Cytochrome c, mono- and diheme variants. | 0.720 |
| ISM_04860 | ISM_10456 | ISM_04860 | ISM_10456 | WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat. | COG2010 Cytochrome c, mono- and diheme variants. | 0.720 |
| ISM_04860 | ISM_13230 | ISM_04860 | ISM_13230 | WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat. | COG2010 Cytochrome c, mono- and diheme variants. | 0.720 |
| ISM_04860 | ISM_16860 | ISM_04860 | ISM_16860 | WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.717 |
| ISM_04860 | ISM_17500 | ISM_04860 | ISM_17500 | WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat. | Probable c-type cytochrome; COG2010 Cytochrome c, mono- and diheme variants. | 0.720 |
| ISM_08180 | ISM_00035 | ISM_08180 | ISM_00035 | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | Hypothetical protein; COG0457 FOG: TPR repeat. | 0.401 |
| ISM_08180 | ISM_02565 | ISM_08180 | ISM_02565 | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | Hypothetical protein; COG2010 Cytochrome c, mono- and diheme variants. | 0.597 |