Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_16930COG0174 Glutamine synthetase. (443 aa)    
Predicted Functional Partners:
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
  
 
 0.933
ISM_16940
FwdC/FmdC family protein; COG0070 Glutamate synthase domain 3.
 
 
 0.920
ISM_16945
Glutamine amidotransferase, class II; COG0067 Glutamate synthase domain 1.
 
  
 0.920
ISM_16935
COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.
 
 
 0.917
carB
COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.
  
 0.877
glmS
D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.872
carA
COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family.
  
 
 0.866
ISM_12965
COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.864
ISM_06105
COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 
 0.863
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
    
 0.858
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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