STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_17000Nitrate/nitrite regulatory protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (219 aa)    
Predicted Functional Partners:
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
  
 0.977
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
   
 0.948
ISM_00215
Hypothetical protein; COG2199 FOG: GGDEF domain.
 
 
 0.829
ISM_04775
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
   
 0.776
ISM_05545
Histidine kinase/response regulator hybrid protein; COG2202 FOG: PAS/PAC domain.
   
 0.776
ISM_01205
Sensor histidine kinase; COG0591 Na+/proline symporter.
   
 0.748
ISM_04780
PAS; COG0642 Signal transduction histidine kinase.
   
 0.741
ISM_12885
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
   
 0.741
ISM_15790
Transcriptional regulator, LuxR family/hydrolase, alpha/beta fold family; COG2771 DNA-binding HTH domain-containing proteins.
  
 0.706
ISM_00035
Hypothetical protein; COG0457 FOG: TPR repeat.
    
 0.705
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.