STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISM_17010COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (325 aa)    
Predicted Functional Partners:
ISM_17005
Probable serine-glyoxylate aminotransferase; COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.
 
 
 0.872
ISM_06675
Phosphate acetyltransferase; COG0281 Malic enzyme.
   
 0.771
ISM_09586
Malate dehydrogenase; COG0281 Malic enzyme.
   
 0.771
ISM_05350
Hydroxypyruvate reductase; COG2379 Putative glycerate kinase.
 
 0.708
ISM_17015
COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
 
  
 0.693
ISM_06040
Formate dehydrogenase, beta subunit; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.
   
 
 0.685
ISM_04010
Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases.
   
 0.661
ISM_03915
2-oxoisovalerate dehydrogenase beta subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
  
 
 0.647
ISM_14700
COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.
     
 0.647
ISM_16955
Possible 2-oxoisovalerate dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
  
 
 0.647
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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