STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_17055COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase. (301 aa)    
Predicted Functional Partners:
ISM_17065
Oxidoreductase, NAD-binding site; COG0665 Glycine/D-amino acid oxidases (deaminating).
 
  
  0.938
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
 
 0.899
ISM_17060
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
 
  0.880
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.828
ISM_12920
COG0460 Homoserine dehydrogenase.
 
 
 0.723
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
  
0.598
ISM_08690
Conserved hypothetcial protein; COG0665 Glycine/D-amino acid oxidases (deaminating).
 
  
  0.595
ISM_01035
Hypothetical protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.
  
 
  0.585
ISM_08835
COG1605 Chorismate mutase.
  
  
 0.553
ISM_01375
Aspartate kinase, monofunctional class; COG0527 Aspartokinases; Belongs to the aspartokinase family.
 
 
 0.550
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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