Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_17065Oxidoreductase, NAD-binding site; COG0665 Glycine/D-amino acid oxidases (deaminating). (448 aa)    
Predicted Functional Partners:
ISM_17055
COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase.
 
     0.930
ISM_17060
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
 
 
  0.891
ISM_09346
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
  
 0.770
ISM_09661
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
  
 0.770
ISM_12990
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
  
 0.770
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
  
 
 0.616
ISM_06330
COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family.
  
     0.567
ISM_00980
Bacterial luciferase family protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
  
     0.529
ISM_04300
Putative aminomethyltransferase protein; Belongs to the GcvT family.
   
  0.522
ISM_15390
Putative aminomethyltransferase protein; Belongs to the GcvT family.
   
  0.522
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (20%) [HD]