STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_17155Metallopeptidase, family M24; COG0006 Xaa-Pro aminopeptidase. (375 aa)    
Predicted Functional Partners:
ISM_17160
Diaminopropionate ammonia-lyase; COG1171 Threonine dehydratase.
 
  
 0.937
ISM_14650
Asp/Glu/Hydantoin racemase family protein; COG3473 Maleate cis-trans isomerase.
 
     0.770
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.634
ISM_09351
COG4583 Sarcosine oxidase gamma subunit.
  
  
  0.552
ISM_10266
Dimethylglycine dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.
  
 0.533
ISM_07890
Polyamine ABC trasnporter, periplasmic polyamine-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.
  
    0.523
ISM_13925
Succinylglutamate desuccinylase/aspartoacylase; COG3608 Predicted deacylase.
    
 0.523
ISM_14100
Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.
  
 0.523
ISM_09346
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
  
 0.518
ISM_09661
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
  
 0.518
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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