| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_03095 | ISM_13465 | ISM_03095 | ISM_13465 | COG0498 Threonine synthase. | Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.447 |
| ISM_03095 | ISM_15265 | ISM_03095 | ISM_15265 | COG0498 Threonine synthase. | COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.630 |
| ISM_03095 | ISM_17160 | ISM_03095 | ISM_17160 | COG0498 Threonine synthase. | Diaminopropionate ammonia-lyase; COG1171 Threonine dehydratase. | 0.637 |
| ISM_03095 | ilvD | ISM_03095 | ISM_08925 | COG0498 Threonine synthase. | COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.591 |
| ISM_03095 | leuB | ISM_03095 | ISM_10241 | COG0498 Threonine synthase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.567 |
| ISM_10521 | ISM_17160 | ISM_10521 | ISM_17160 | COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. | Diaminopropionate ammonia-lyase; COG1171 Threonine dehydratase. | 0.800 |
| ISM_13465 | ISM_03095 | ISM_13465 | ISM_03095 | Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | COG0498 Threonine synthase. | 0.447 |
| ISM_13465 | ISM_15265 | ISM_13465 | ISM_15265 | Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.476 |
| ISM_13465 | ISM_17160 | ISM_13465 | ISM_17160 | Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Diaminopropionate ammonia-lyase; COG1171 Threonine dehydratase. | 0.609 |
| ISM_14650 | ISM_17155 | ISM_14650 | ISM_17155 | Asp/Glu/Hydantoin racemase family protein; COG3473 Maleate cis-trans isomerase. | Metallopeptidase, family M24; COG0006 Xaa-Pro aminopeptidase. | 0.772 |
| ISM_14650 | ISM_17160 | ISM_14650 | ISM_17160 | Asp/Glu/Hydantoin racemase family protein; COG3473 Maleate cis-trans isomerase. | Diaminopropionate ammonia-lyase; COG1171 Threonine dehydratase. | 0.677 |
| ISM_14700 | ISM_15265 | ISM_14700 | ISM_15265 | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.790 |
| ISM_14700 | ISM_17160 | ISM_14700 | ISM_17160 | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Diaminopropionate ammonia-lyase; COG1171 Threonine dehydratase. | 0.652 |
| ISM_14700 | leuB | ISM_14700 | ISM_10241 | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.794 |
| ISM_14700 | mdh | ISM_14700 | ISM_05055 | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.850 |
| ISM_15265 | ISM_03095 | ISM_15265 | ISM_03095 | COG0440 Acetolactate synthase, small (regulatory) subunit. | COG0498 Threonine synthase. | 0.630 |
| ISM_15265 | ISM_13465 | ISM_15265 | ISM_13465 | COG0440 Acetolactate synthase, small (regulatory) subunit. | Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.476 |
| ISM_15265 | ISM_14700 | ISM_15265 | ISM_14700 | COG0440 Acetolactate synthase, small (regulatory) subunit. | COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits. | 0.790 |
| ISM_15265 | ISM_17160 | ISM_15265 | ISM_17160 | COG0440 Acetolactate synthase, small (regulatory) subunit. | Diaminopropionate ammonia-lyase; COG1171 Threonine dehydratase. | 0.670 |
| ISM_15265 | ilvD | ISM_15265 | ISM_08925 | COG0440 Acetolactate synthase, small (regulatory) subunit. | COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.960 |