Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_17520COG1230 Co/Zn/Cd efflux system component. (266 aa)    
Predicted Functional Partners:
ISM_17530
Putative RND efflux system protein; COG1230 Co/Zn/Cd efflux system component.
 
 
 
 0.729
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
    0.683
ISM_17525
Hypothetical protein; COG1305 Transglutaminase-like enzymes, putative cysteine proteases.
 
     0.671
ISM_17575
Hypothetical protein; COG0428 Predicted divalent heavy-metal cations transporter.
 
   
 0.461
ISM_17565
COG0739 Membrane proteins related to metalloendopeptidases.
 
     0.406
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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