Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_17630Iron dependent repressor; COG1321 Mn-dependent transcriptional regulator. (150 aa)    
Predicted Functional Partners:
ISM_14165
High-affinity zinc uptake system membrane protein ZnuB; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components.
  
 
 0.745
znuC
Zinc ABC transporter, ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
  
 
 0.703
ISM_17640
COG0428 Predicted divalent heavy-metal cations transporter.
 
  
 0.633
fur-2
Ferric-uptake regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.
  
  
 0.533
ISM_17635
COG2132 Putative multicopper oxidases.
 
     0.511
ISM_13805
COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
   
    0.509
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.423
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (22%) [HD]