STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_17685RepA partitioning protein/ATPase, ParA type; COG1192 ATPases involved in chromosome partitioning. (395 aa)    
Predicted Functional Partners:
ISM_17690
Rep B partitioning protein/ParB-like protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.
 
 
 0.991
ISM_17695
Replication initiator RepC.
 
   
 0.898
ISM_06715
Chromosome partitioning protein parB; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.
 
 
 0.859
ISM_17730
ParB-like nuclease; COG1475 Predicted transcriptional regulators.
 
 
 0.855
dnaA
Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
 
 0.654
ISM_00520
Hypothetical protein; COG0593 ATPase involved in DNA replication initiation.
  
 
 0.609
ISM_17660
Hypothetical protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component.
  
     0.588
ISM_17680
SpoVT/AbrB-like cell growth regulatory protein; COG2336 Growth regulator.
 
     0.566
ISM_17675
Hypothetical memebrane protein; COG5573 Predicted nucleic-acid-binding protein, contains PIN domain.
 
     0.556
ISM_00630
Hypothetical protein.
    
   0.548
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.