STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_17795Y4BN. (787 aa)    
Predicted Functional Partners:
ISM_17790
COG0464 ATPases of the AAA+ class.
 
  
 0.910
secY
Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.891
ISM_03100
SURF1 family protein.
    
   0.887
ISM_10091
Trypsin; COG5640 Secreted trypsin-like serine protease.
  
 0.843
ISM_14560
Type I secretion target repeat protein; COG2931 RTX toxins and related Ca2+-binding proteins.
 
 0.808
ISM_10126
FtsK/SpoIIIE family protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins.
  
 
 0.756
ISM_00630
Hypothetical protein.
  
 0.755
ISM_00635
Type I secretion target repeat protein.
  
 0.755
ISM_00705
Putative RTX family exoprotein; COG2931 RTX toxins and related Ca2+-binding proteins.
  
 0.755
ISM_01770
Hypothetical protein; COG0480 Translation elongation factors (GTPases).
  
 0.755
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.