STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A306_00000376DUF4203 domain-containing protein. (323 aa)    
Predicted Functional Partners:
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.786
A306_00002661
Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
   
 0.677
APPL1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.669
APPL2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.669
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.665
MIB2
Mindbomb E3 ubiquitin protein ligase 2, transcript variant X1.
    
 0.620
BOK
BCL2-related ovarian killer, transcript variant X1.
    
 0.534
RIPK4
Receptor-interacting serine-threonine kinase 4.
    
 0.499
CENPN
Centromere protein N.
   
 0.494
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.462
Your Current Organism:
Columba livia
NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon
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