A306_00014970 protein (Columba livia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A306_00014970

Heat shock factor protein 1-like. (293 aa)

Predicted Functional Partners:

HSP90AB1

0.651

HSP90AA1

0.651

PTGES3

0.627

SMG1

0.624

MAPK1

0.604

SIRT1

0.597

TSC1

0.590

TRAP1

0.590

GSK3B

0.584

HSBP1L1

0.577

Your Current Organism:

Columba livia

NCBI taxonomy Id: 8932
Other names: C. livia, Columba domestica, Columba livia domestica, carrier pigeon, domestic pigeon, rock dove, rock pigeon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A306_00014970	GSK3B	A0A2I0LIP2	A0A2I0MLE4	Heat shock factor protein 1-like.	Glycogen synthase kinase 3 beta, transcript variant X1; Belongs to the protein kinase superfamily.	0.584
A306_00014970	HSBP1L1	A0A2I0LIP2	A0A2I0LSU9	Heat shock factor protein 1-like.	Heat shock factor binding protein 1-like 1.	0.577
A306_00014970	HSP90AA1	A0A2I0LIP2	A0A2I0MNU1	Heat shock factor protein 1-like.	Heat shock protein 90kDa alpha (Cytosolic), class A member 1.	0.651
A306_00014970	HSP90AB1	A0A2I0LIP2	A0A2I0MAK6	Heat shock factor protein 1-like.	Heat shock protein 90kDa alpha (Cytosolic), class B member 1.	0.651
A306_00014970	MAPK1	A0A2I0LIP2	A0A2I0M868	Heat shock factor protein 1-like.	Mitogen-activated protein kinase 1, transcript variant X2.	0.604
A306_00014970	PTGES3	A0A2I0LIP2	A0A2I0LJ55	Heat shock factor protein 1-like.	Prostaglandin E synthase 3 (Cytosolic).	0.627
A306_00014970	SIRT1	A0A2I0LIP2	A0A2I0MF05	Heat shock factor protein 1-like.	Sirtuin 1, transcript variant X1.	0.597
A306_00014970	SMG1	A0A2I0LIP2	A0A2I0M4F2	Heat shock factor protein 1-like.	SMG1 phosphatidylinositol 3-kinase-related kinase; Belongs to the PI3/PI4-kinase family.	0.624
A306_00014970	TRAP1	A0A2I0LIP2	A0A2I0M496	Heat shock factor protein 1-like.	TNF receptor-associated protein 1.	0.590
A306_00014970	TSC1	A0A2I0LIP2	A0A2I0M3U1	Heat shock factor protein 1-like.	Tuberous sclerosis 1, transcript variant X1.	0.590
GSK3B	A306_00014970	A0A2I0MLE4	A0A2I0LIP2	Glycogen synthase kinase 3 beta, transcript variant X1; Belongs to the protein kinase superfamily.	Heat shock factor protein 1-like.	0.584
GSK3B	HSP90AA1	A0A2I0MLE4	A0A2I0MNU1	Glycogen synthase kinase 3 beta, transcript variant X1; Belongs to the protein kinase superfamily.	Heat shock protein 90kDa alpha (Cytosolic), class A member 1.	0.412
GSK3B	HSP90AB1	A0A2I0MLE4	A0A2I0MAK6	Glycogen synthase kinase 3 beta, transcript variant X1; Belongs to the protein kinase superfamily.	Heat shock protein 90kDa alpha (Cytosolic), class B member 1.	0.412
GSK3B	TRAP1	A0A2I0MLE4	A0A2I0M496	Glycogen synthase kinase 3 beta, transcript variant X1; Belongs to the protein kinase superfamily.	TNF receptor-associated protein 1.	0.405
GSK3B	TSC1	A0A2I0MLE4	A0A2I0M3U1	Glycogen synthase kinase 3 beta, transcript variant X1; Belongs to the protein kinase superfamily.	Tuberous sclerosis 1, transcript variant X1.	0.937
HSBP1L1	A306_00014970	A0A2I0LSU9	A0A2I0LIP2	Heat shock factor binding protein 1-like 1.	Heat shock factor protein 1-like.	0.577
HSBP1L1	HSP90AA1	A0A2I0LSU9	A0A2I0MNU1	Heat shock factor binding protein 1-like 1.	Heat shock protein 90kDa alpha (Cytosolic), class A member 1.	0.445
HSBP1L1	HSP90AB1	A0A2I0LSU9	A0A2I0MAK6	Heat shock factor binding protein 1-like 1.	Heat shock protein 90kDa alpha (Cytosolic), class B member 1.	0.445
HSBP1L1	TRAP1	A0A2I0LSU9	A0A2I0M496	Heat shock factor binding protein 1-like 1.	TNF receptor-associated protein 1.	0.400
HSBP1L1	TSC1	A0A2I0LSU9	A0A2I0M3U1	Heat shock factor binding protein 1-like 1.	Tuberous sclerosis 1, transcript variant X1.	0.400